Scientific publications

Articles in scientific journals

  1. Rischke H, Nestle U, Fechter T, Doll C, Volegova-Neher N, Henne K, Scholber J, Knippen S, Kirste S, Grosu A, Jilg C. “3 Tesla multiparametric MRI for GTV-definition of dominant intraprostatic lesions in patients with prostate cancer – an interobserver variability study”. Radiation Oncology, 8:183, 2013. [Available here]
  2. Deviers A, Ken S, Filleron T, Rowland B, Laruelo A, Catalaa I, Lubrano V, Celsis P, Berry I, Mogicato G, Moyal Cohen-Jonathan E, Laprie A. “Evaluation of Lactate/N-acetylaspartate ratio, defined with MR Spectroscopic Imaging before radiotherapy, as a new predictive marker of the site of relapse in patients with glioblastoma multiforme”.  Int J Radiat Oncol Biol Phys, 90(2): 385-393, October 2014. [Available here]
  3. Dolz J, Massoptier L, Vermandel M, “Segmentation algorithms of subcortical brain structures on MRI for radiotherapy and radiosurgery: a survey”.  Journal of Innovation and Research in BioMedical Engineering, IRBM. 36,200-212, June 2015. [Available here]
  4. de Pasquale F, Falletta Caravasso C, Péran P, Catani S, Tuovinen N, Sabatini U, Formisano R. “Functional Magnetic Resonance Imaging in disorders of Consciousness: preliminary results of an innovative analysis of brain connectivity”. Funct Neurol, 30(3): 193-201, July 2015. [Available here]
  5. Dolz J, Laprie A, Ken S, Leroy HA, Reyns N, Massoptier L, Vermandel M. “Supervised machine learning-based classification scheme to segment the brainstem on MRI in multicenter brain tumor treatment context”. Int J Comput Assist Radiol Surg, pp.1-9, July 2015. [Available here]
  6. Fechter T, Dolz J, Chirindel A, Schlachter M, Carles M, Adebahr S, Mix M, Nestle U. “Fully Automatic Danger Zone Determination for SBRT in NSCLC”. Journal of Radiation Oncology Informatics, 7(1): 1-27, July 2015. [Available here]
  7. Carles M, Fechter T, Nemer U, Nanko N, Mix M, Nestle U, Schaefer A. “Feasibility of a semi-automated contrast-oriented algorithm for tumor segmentation in retrospectively gated PET images: phantom and clinical validation”. Phys Med Biol, 60(24):9227-9251, November 2015. [Available here]
  8. Zamboglou C, Wieser G, Hennies S, Rempel I, Kirste S, Soschynski M, Rischke HC, Fechter T, Jilg CA, Langer M, Meyer PT, Bock M, Grosu AL. “MRI versus 68Ga-PSMA PET/CT for gross tumour volume delineation in radiation treatment planning of primary prostate cancer”. Eur J Nucl Med Mol Imaging, November 2015. [Available here]
  9. Ramkumar A, Dolz J, Kirisli HA, Adebahr S, Schimek-Jasch T, Nestle U, Massoptier L, Varga E, Stappers PJ, Niessen WJ, Song Y. “User interactions in semi-automatic segmentation of organs at risk: a case study in radiotherapy”. Journal of Digital Imaging, 29:264-277, 2016. [Available here]
  10. Dolz J, Betrouni N, Quidet M, Kharroubi D, Leroy HA, Reyns N, Massoptier L, Vermandel M. “Stacking Denoising auto-encoders in a deep network to segment the brainstem on MRI in brain cancer patients: a clinical study”. Journal of Computerized Medical Imaging and Graphics (CMIG), in press, 2016
  11. Dolz J, Kirisli HA, Fechter T, Karnitzki S, Oehlke O, Nestle U, Vermandel M, Massoptier L. “Interactive contour delineation of organs at risk in radiotherapy: clinical evaluation on NSCLC patients”. Medical Physics, in press, 2016.
  12. Laruelo A, Chaari L, Tourneret JY, Batatia H, Ken S, Rowland B, Ferrand R, Laprie A. “Spatio-spectral regularization to improve MRSI quantification”, NMR Biomed, 2016.
  13. Hauler F, Furtado H, Jurisic M, Polanec SH, Spick C, Laprie A, Nestle U, “Automatic quantification of multi-modal rigid registration accuracy using feature detectors”, Phys Med Biol, in press, 2016.
  14. Schlachter M, Fechter T, Jurisic M, Schimek Jasch T, Oehlke O, Adebahr S, Birkfellner W, Nestle U, Bühler K. “Visualization of Deformable Image Registration Quality using Local Image Dissimilarity”, submitted to IEEE Transactions on Medical Imaging (second revision).

Poster and paper in conferences

  1. Massoptier L, Birkfellner W, Nestle U, Laprie A, Sabatini U, Buehler K, Freudenthal A. “Multimodal morphologic and functional images for radiotherapy by the research training network called SUMMER”. Int Symp Biomed Imag (ISBI’12 – Barcelona), 1:506, May 2012.
  2. Hauler F, Furtado H, Jurisić M, Birkfellner W. “Image registration of PET/CT and MRI”. 2013 IEEE Signal Processing Society (SPS) Summer School on Biomedical Image Processing and Analysis (SSBIPA’13), June 2013.
  3. Laruelo A, Chaari L, Batatia H, Ken S, Rowland B, Laprie A, Tourneret JY. “Hybrid sparse regularization for magnetic resonance spectroscopy”. 35th IEEE Int Conf Eng Med Biol (EMBC’13 – Osaka), 1:6768 – 6771, July 2013.
  4. Ramkumar A, Varga E, Laprie A, Niessen WJ, Freudenthal A. “A pilot study of Pen-Tablet interaction in radiotherapy contouring using orthogonal and non-orthogonal views”. Design of Medical Devices Conf – Europe (DMD’13 – Delft), 1:44-50, October 2013.
  5. Aselmaa A, Goossens RHM, Freudenthal A. “What is sensemaking in the context of external radiotherapy treatment planning?” Design of Medical Devices Conf – Europe (DMD’13 – Delft), 1:51-58, October 2013.
  6. Fechter T, Mix M, Gardin I, Papke T, Schimek-Jasch T, Meyer P, Grosu A, Nestle U. “Malignant glioma delineation in amino acid PET-images using a 3D random walk approach”. Int J Radiat Oncol Biol Phys (55th ASTRO meeting), 87(2):S622, October 2013.
  7. Schanne DH, Schumm K, Mix M, Duncker-Rohr V, Fechter T, Meyer PT, Grosu AL, Nestle U. “Pulmonary changes in FDG-PET/CT after cure of small lung tumors with stereotactic ablative radiotherapy: which imaging features can be expected?”. Int J Radiat Oncol Biol Phys (55th ASTRO meeting), 87(2):S534, October 2013.
  8. Christ U, Fechter T, Mix M, Hennig J, Nestle U. “Automatic background determination for contrast-based threshold segmentation in PET imaging based on histograms”. EANM’13 (Lyon), Eur J Nucl Med Mol Imaging, 40(S2), October 2013.
  9. Deviers A, Ken S, Rowland B, Laruelo A, Filleron T, Franceries X, Berry I, Celsis P, Mogicato G, Moyal Cohen-Jonathan E, Laprie A. “Assessment of MR Diffusion and Spectroscopy as predictive markers of local site of relapse in Glioblastoma”. 30th Annual Scientific Meeting of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB’13).
  10. Laruelo A, Chaari L, Rowland B, Ken S, Batatia H, Ferrand R, Tourneret JY, Laprie A. “MRSI data denoising to improve metabolite quantification”. 30th Annual Scientific Meeting of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB’13), 2:470-471, October 2013.
  11. Rowland B, Deviers A, Ken S, Laruelo A, Ferrand R, Simon L, Laprie A. “Beyond the metabolic map: an alternative perspective on MRSI data”. 30th Annual Scientific Meeting of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB’13), 1:270, October 2013.
  12. Dolz J, Kirisli HA, Viard R, Massoptier L. “Fast interactive approach to segment organs at risk in radiotherapy treatment planning”. SPIE Medical Imaging, February 2014.
  13. Dolz J, Kirisli HA, Viard R, Massoptier L. “Combining watershed and graph cuts methods to segment OARs in radiotherapy”. SPIE Medical Imaging, February 2014.
  14. Dolz J, Kirisli HA, Jurisic M, Fechter T, Christ U, Adebahr S, Mix M, Birkfellner W, Massoptier L, Nestle U. “Minimally interactive OAR and GTV segmentation in 4D FDG-18 PET/CT NSCLC: first clinical experience”. ESTRO, April 2014.
  15. Schlachter M, Fechter T, Bühler K, Nestle U. “Fast visual quality inspection of 4D PET/CT contouring of manual and semi-automatic contours”. ESTRO, April 2014.
  16. Tuovinen N, Hamamci A, de Pasquale F, Sabatini U. “Identification of regions at risk for radiotherapy planning based on fMRI data”. ESTRO, April 2014.
  17. Tuovinen N, Hamamci A, de Pasquale F, Sabatini U. “Postoperative brain tumor resting state and task fMRI study for radiotherapy planning”. Joint annual meeting ISMRM-ESMRMB in Milan, May 2014.
  18. Rowland B, Laruelo A, Ken S, Tourneret J-Y, Laprie A. “Baseline estimation in MR spectroscopy using frequency dependent non-quadratic cost functions”. ISMRM-ESMRMB 2014 in Milan, May 2014.
  19. Hauler F, Jurisic M, Furtado H, Nestle U, Birkfellner W. “Automated evaluation of multi-modal image rigid registration”. CARS Conference in Japan, June 2014.
  20. Tuovinen N, Hamamci A, de Pasquale F, Laprie A, Sabatini U.  “Resting-state network plasticity in the presence of brain tumors”. 20th Meeting of Organization for Human Brain Mapping (OHBM), June 2014.
  21. Ramkumar A, Varga E, Niessen WJ, Laprie A, Rowland B, Freudenthal A. “Comparison of heuristic evaluation and think-aloud protocol: A study in radiotherapy contouring software”. Proc. of the 5th Int. Conf. on Applied Human Factors & Ergonomics (July 2014, Krakow).
  22. Aselmaa A, Goossens RHM, Laprie A, Rowland B, Freudenthal A. “Medical factors of brain tumor delineation in radiotherapy for software design”. Proc. of the 5th Int. Conf. on Applied Human Factors & Ergonomics (July 2014, Krakow).
  23. Schlachter M, Fechter T, Nestle U, Bühler K. “Visualization of 4D-PET/CT, Target Volumes and Dose Distribution: Applications in Radiotherapy Planning”. Int Conf Med Image Comput Comput Assist Interv, IGART workshop (MICCAI’14), September 2014.
  24. Fechter T, Dolz J, Kirisli HA, Chirindel A, Adebahr S, Schimek-Jasch T, Vermandel M, Massoptier L, Nestle U. “Evaluation of an Integrated Minimally Interactive Tool for the Segmentation of Relevant OAR in Lung Cancer.” ASTRO’s 56th annual meeting: S817, September 2014.
  25. Kraft J, Fechter T, Götz I, Papke T, Lemarignier C, Modzelewski R, Chirindel A, Gardin I, Grosu AL, Nestle U. “Evaluation and Comparison of Segmentation Algorithms in Low Contrast FET-PET Scans for Gross Tumor Volume Delination”.  ASTRO’s 56th annual meeting, September 2014.
  26. Laruelo A, Chaari L, Ken S, Rowland B, Batatia H, Ferrand R, Simon L, Tourneret J, Laprie A. “Towards accurate and robust MRSI quantification to improve the radiotherapy treatment of GBM”. Int J Radiat Oncol Biol Phys (56th ASTRO meeting), September 2014.
  27. Jurisic M, Fechter T, Hauler F, Furtado H, Nestle U, Birkfellner W. “Gauss-Newton Method for Segmentation assisted Deformable Registration”, MIDAS Journal – Image-Guided Adaptive Radiation Therapy (IGART), October 2014.
  28. Hauler F, Jurisic M, Furtado H, Sabatini U, Laprie A, Nestle U, Birkfellner W. “Automatic accuracy measurement for multi-modal rigid registration using feature descriptors”, MIDAS Journal – Image-Guided Adaptive Radiation Therapy (IGART),  October 2014.
  29. Carles M, Fechter T, Christ U, Nanko N, Schaefer A, Mix M, Nestle U. “Validation of a 4D PET tumor segmentation algorithm with experimental phantom measurements”. EANM Congress, October 2014.
  30. Carles M, Fechter T, Christ U, Schaefer A, Mix M, Nestle U. “4D PET Tumor Segmentation Algorithm Evaluation with Experimental Phantom Measurements”. 21st IEEE Nuclear Science Symp & Med Imaging Conf (NSS/MIC’14), November 2014.
  31. Carles M, Chirindel A, Fechter T, Christ U, Schaefer A, Mix M, Nestle U. “4D FDG-PET Quantification in Thoracic Anatomical Structures for Anthropomorphic Phantom Measurements”. 21st IEEE Nuclear Science Symp & Med Imaging Conf (NSS/MIC’14), November 2014.
  32. Nunes M, Matkovic K, Bühler K. “Convex Hull Brushing in Scatter Plots – Multi-Dimensional Correlation Analysis”, IVAPP, Berlin, March 2015.
  33. Nunes M, Laruelo A, Ken S, Laprie A, Bühler K. “A Survey on Visualizing Magnetic Resonance Spectroscopy Data”. Proc. Eurographics Workshop on Visual Computing for Biology and Medicine, 2014.
  34. Nunes M, Rowland B, Schlachter M, Ken S, Matkovic K, Laprie A, Bühler K. “An Integrated Visual Analysis System for Fusing MR Spectroscopy and Multi-Modal Radiology Imaging”. Proc. IEEE VAST 2014.
  35. Tuovinen N, de Pasquale F, Falletta Caravasso C, Giudice E, Miceli R, Ingrosso G, Santoni R, Sabatini U. ”Topological Re-organization of Functional Connectivity at Rest in Brain Tumor Patients”, European conference on clinical neuroimaging ECCN in Rome, March 2015.
  36. Nunes M, Matkovic, K, Bühler K. “Convex Hull Brushing in Scatter Plots – Multi-Dimensional Correlation Analysis”. Proceedings of VISAPP, March 2015.
  37. Dolz J, Leroy HA, Reyns N, Massoptier L, Vermandel M. “A fast and fully automated approach to segment optic nerves on MRI and its application to radiosurgery”. IEEE International Symposium on Biomedical Imaging (ISBI), pp. 1102-1105, April 2015.
  38. Carles M, Fechter T, Nemer C, Schaefer A, Mix M, Nestle U. “Tumor contour in 4D-PET: algorithm performance for different target movement, volume and heterogeneity”. 3Rd ESTRO Forum, April 2015.
  39. Rowland B, Laruelo A, Lin AP, Ken S. “MRS Choline/NAA enhancement is a predictor of post-RT disease-free survival time in glioblastoma multiforme”, ESTRO 2015.
  40. Tuovinen N, de Pasquale F, Falletta Caravasso C, Giudice E, Miceli R, Ingrosso G, Santoni R, Sabatini U. ”Functional Connectivity Changes in the Presence of Brain Tumors”, ISMRM in Toronto, May 2015.
  41. Laruelo A, Chaari L, Tourneret JY, Batatia H, Ken S, Rowland B, Ferrand R, Laprie A, “Segmentation of radiotherapy target volumes based on magnetic resonance spectroscopic imaging”,  3rd Int Mag Res in RT Symposium (MRinRT), June 2015.
  42. Tuovinen N, de Pasquale F, Falletta Caravasso C, Giudice E, Miceli R, Ingrosso G, Santoni R, Sabatini U. ”Topological Re-organization of Functional Connectivity at Rest in Brain Tumor Patients”, 21st Meeting of Organization for Human Brain Mapping (OHBM), 2015.
  43. Dolz J, Ken S, Leroy HA, Reyns N, Laprie A, Massoptier L, Vermandel M. “Supervised machine learning method to segment the brainstem on MRI in multicenter brain tumor treatment context”. Int Conf on Comput Assist Radiol Surg (CARS), 2015.
  44. Laruelo A, Chaari L, Ken S, Tourneret JY, Batatia H, Laprie A, “MRSI data unmixing using spatial and spectral priors in transformed domains”, Proc. IEEE Int Symp Biomed Imag (ISBI), 2016.
  45. Tuovinen N, de Pasquale F, Falletta Caravasso C, Giudice E, Miceli R, Ingrosso G, Santoni R, Sabatini U. Brain Connectivity Changes in the Presence of a Glioblastoma, e-Poster 1882, ESTRO 2016.
  46. Tuovinen N, de Pasquale F, Falletta Caravasso C, Giudice E, Miceli R, Ingrosso G, Santoni R, Sabatini U. Functional Brain Connectivity in Glioblastoma Patients Pre- and Post-Radiotherapy, e-Poster 1883, ESTRO 2016.
  47. Dolz J, Kirisli HA, Fechter T, Karnitzki S, Nestle U, Vermandel M, Massoptier L. “Preliminary clinical study to evaluate an interactive system to segment OARs in thoracic oncology”, poster PO-0932, ESTRO 2016.(nominated for the ESTRO Best Poster Award in the category: ‘Physics Poster Award’)
  48. Laruelo A, Dolz J, Ken S, Chaari L, Vermandel M, Massoptier L, Laprie A. “Probability map prediction of relapse areas in glioblastoma patients using multi-parametric MR”, poster PV-0475, ESTRO 2016 (nominated for the ESTRO Best Poster Award in the category: ‘Physics Poster Award’)
  49. Ramkumar A, Song Y, Niessen WJ, Stappers PJ. “How think-aloud and heuristic methods can help in identifying the design issues in the current segmentation systems?” HFES 2016. SUBMITTED

Book chapters

  1. Nunes M, Schlachter M, Bühler K. “Visualization tools for radiotherapy – a survey”. Innovative imaging to improve radiotherapy treatments, Lulu Enterprises Inc Ed, 1:21-28, July 2013.
  2. Ramkumar A, Varga E, Niessen WJ, Freundethal A. “Exploring input devices for contouring in external radiotherapy”. Innovative imaging to improve radiotherapy treatments, Lulu Enterprises Inc Ed, 1:29-34, July 2013.
  3. Dolz J, Viard R, Massoptier L. “The use of watershed and graph-cuts methods to segment OARs in radiotherapy”. Innovative imaging to improve radiotherapy treatments, Lulu Enterprises Inc Ed, 1:35-40, July 2013.
  4. Tuovinen N. “Role of MR-Imaging for brain tumors”. Innovative imaging to improve radiotherapy treatments, Lulu Enterprises Inc Ed, 1:69-78, July 2013.
  5. Rowland B, Laruelo A, Ken S, Ferrand R, Laprie A. “Water suppression in post-processing of MRSI signals”. Innovative imaging to improve radiotherapy treatments, Lulu Enterprises Inc Ed, 1:77-84, July 2013.
  6. Fechter T, Nestle U. “PET-image segmentation using random walks”. Innovative imaging to improve radiotherapy treatments, Lulu Enterprises Inc Ed, 1:85-90, July 2013.
  7. Aselmaa A, Goossens RHM, Laprie A, Ramkumar A, Ken S, Freudenthal A. “External radiotherapy treatment planning – situation today and perspectives for tomorrow”. Innovative imaging to improve radiotherapy treatments, Lulu Enterprises Inc Ed, 1:91-98, July 2013.
  8. Hauler F, Andrzejewski P, Furtado H, Birkfellner W. “Image registration of PET/CT and MR”. Innovative imaging to improve radiotherapy treatments, Lulu Enterprises Inc Ed, 1:109-114, July 2013.
  9. Laruelo A, Chaari L, Batatia H, Rowland B, Ken S, Ferrand R, Tourneret JY, Laprie A. “Magnetic resonance spectroscopic data processing”. Innovative imaging to improve radiotherapy treatments, Lulu Enterprises Inc Ed, 1:115-120, July 2013.
  10. Jurisic M, Furtado H, Birkfellner W. “Visualization of deformable image registration using MITK”. Innovative imaging to improve radiotherapy treatments, Lulu Enterprises Inc Ed, 1:121-126, July 2013.
  11. Freudenthal A, Aselmaa A, Ramkumar A, Laprie A, Massoptier L. “Human Factors Engineering for Radiotherapy planning software”. Innovative imaging to improve radiotherapy treatments, Lulu Enterprises Inc Ed, 1:129-134, July 2013.
  12. Aselmaa A, Song Y, Goossens R. “Design challenges in incorporating segmentation methods into radiotherapy software”. Multimodal imaging towards individualized radiotherapy treatments, Editors: Massoptier and Song, pp. 5-11, July 2014.
  13. Jurisic M, Hauler F, Furtado H, Birkfellner W. “Diffusion registration of Lung CT”. Multimodal imaging towards individualized radiotherapy treatments, Editors: Massoptier and Song, pp. 12-16, July 2014.
  14. Hauler F, Jurisic M, Furtado H, Nestle U, Birkfellner W. “Automated evaluation of multi-modal image rigid registration”. Multimodal imaging towards individualized radiotherapy treatments, Editors: Massoptier and Song, pp. 17-23, July 2014.
  15. Dolz J, Kirisli HA, Vermandel M, Massoptier L. “Subcortical structures segmentation on MRI using support vector machines”. Multimodal imaging towards individualized radiotherapy treatments, Editors: Massoptier and Song, pp. 24-31, July 2014.
  16. Carles M, Fechter T, Christ U, Chirindel A, Schaefer A, Mix M, Nestle U.  “Evaluation of 4D PET tumour segmentation algorithm with dynamic experimental phantom measurements”. Multimodal imaging towards individualized radiotherapy treatments, Editors: Massoptier and Song, pp. 32-41, July 2014.
  17. Fechter T, Carles M, Chirindel A, Christ U, Nestle U. “A threshold and region-growing based algorithm for 18FDG-PET 4D GTV delineation”. Multimodal imaging towards individualized radiotherapy treatments, Editors: Massoptier and Song, pp.42-48, July 2014.
  18. Tuovinen N, de Pasquale F, Sabatini U. “fMRI: resting-state networks and task-evoked activations in the presence of brain tumours”. Multimodal imaging towards individualized radiotherapy treatments, Editors: Massoptier and Song, pp. 49-53, July 2014.
  19. Hamamci A, Tuovinen N, de Pasquale F, Sabatini U. “Defining new regions at risk: fiber tractography for planning radiotherapy of brain tumours”. Multimodal imaging towards individualized radiotherapy treatments, Editors: Massoptier and Song, pp. 54-62, July 2014.
  20. Laruelo A, Chaari L, Batatia H, Rowland B, Ken S, Ferrand R, Tourneret JY, Laprie A. “Exploiting MRSI data properties to improve quantification”. Multimodal imaging towards individualized radiotherapy treatments, Editors: Massoptier and Song, pp. 63-68, July 2014.
  21. Ramkumar A, Dolz J, Kirisli HA, Schimek-Jasch T, Adebahr S, Nestle U, Massoptier L, Varga E, Stappers PJ, Niessen WJ, Song Y. “Human computer interaction in segmenting organs at risk for radiotherapy: a pilot study”. Multimodal imaging towards individualized radiotherapy treatments, Editors: Massoptier and Song, pp. 69-79, July 2014.
  22. Nunes M, Rowland B, Schlachter M, Ken S, Matkovic K, Laprie A, Bühler K. “Enabling fast analysis and fusion of  MR spectroscopy imaging”. Multimodal imaging towards individualized radiotherapy treatments, Editors: Massoptier and Song, pp. 90-95, July 2014.
  23. Schlachter M, Fechter T, Nestle U, Bühler K. “4D PET/CT visualization in radiotherapy planning”. Multimodal imaging towards individualized radiotherapy treatments, Editors: Massoptier and Song, pp. 96-100, July 2014.